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Investigators observe how this pentadecapeptide interacts with focal adhesion kinase (FAK) and paxillin cascades to physically guide structural cells to wound sites, balancing local nitric oxide signaling to stabilize endothelial cell survival curves

Eric Topol of Scripps Research Translational Institute was more direct: "These peptides have no data to support their safety and efficacy." The clinical proponents argue that the FDA's safety concerns immunogenicity risk, impurity risk, organ toxicity are theoretically valid but speculative in practice

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