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The kinase activity is not essential for the TRPM7 channel activity, because mutation of two autophosphorylation sites or of a key catalytic site that abolished kinase activity never affected the channel activity (Matsushita et al., 2005)

Therefore, there is an urgent need to develop a simple and rapid method for PMI detection

Treat your peptides with the respect their precision and power demand, and they will yield the clean, reliable data you need