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It is strongly recommended that athletes follow the minimum washout periods, expressed from the time of administration to the start of the in-competition period

Given that HIF-2 is an important transcription factor in cancer progression and leads to poor prognosis 69,70 , these findings suggest that targeting HIF-2 might be an effective therapeutic strategy by inhibiting glutamine metabolism in these notorious cancers

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Frequency: one subcutaneous injection each day , increasing by roughly 100 mcg every 24 weeks as tolerated