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DISCLOSURES REFERENCES SOURCE Polster, H., Kagha, K., & Luke, J

For instance, FLT3-STAT3 signaling directly binds to the PD-L1 promoter and stimulates its transcription, while PRL2 indirectly upregulates PD-L1 through the TLR4-NF-B axis and suppresses the cytotoxic activity of T cells (84)

Furthermore, Figures 5B, C suggest that RGD-GHK evidently suppressed the protein and mRNA level of matrix metalloproteinase-1 (MMP-1) in vitro , which catalyzes the cleavage of collagen