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New findings regarding the link between the thyroid gland and gut microbiome were also explored, and the impact of probiotics with antioxidant properties on thyroid diseases was also assessed

Other measures to target hypoxia include targeting hypoxia-induced signaling pathway proteins (such as HIF-PHD-pVHL pathway proteins and mTOR pathway proteins, etc.) and increasing oxygen supply through vascular normalization (such as the use of antiangiogenic drugs, etc.) (198200) ( Figure 3 )