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Indeed, studies in allergic asthma mice models show oxidative damage of mitochondria in the bronchial epithelium ( Mitochondria play a central role in the regulation of eosinophil apoptosis, as IL-5 and GM-CSF promote eosinophil survival by inhibiting the mitochondrial (intrinsic) pathway of apoptosis ( In this review, we aim to summarise the limited literature currently available on eosinophil mitochondria, particularly their structure and dynamics, role in apoptosis and cellular metabolism and how this facilitates their cellular function

Zigler JE, Guyer RD, Gornet MF, Ferko N, Cameron C, Patel L: Long-Term Outcomes of Lumbar Total Disc Replacement versus Spinal Fusion for the Treatment of DDD: A Novel Meta-Analysis of Randomized Controlled Trials

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