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Most patients describe the discomfort as brief and very tolerable, especially compared to the chronic pain they've been dealing with

Timing Follow-up Marker Blood pressure and resting heart rate Why it matters Adds cardiovascular context because retatrutide may affect heart rate and weight loss can change blood pressure

Notably, while excess iodine is well known to trigger thyroid autoimmunity in susceptible individuals, evidence from the literature is reassuring that an adequate iodine status (defined as a UIC between 100 g/L and 299 g/L) is safe in this regard [25, 26]