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Chen Z-Y, Ieraci A, Teng H, Dall H, Meng C-X, Herrera DG, Nykjaer A, Hempstead BL, Lee FS (2005) Sortilin controls intracellular sorting of brain-derived neurotrophic factor to the regulated secretory pathway

As such, an effective treatment would be expected to augment striatal synaptic connectivity, protect SN neurons from underlying death inducers, and ideally stimulate the replacement of lost SN neurons from preexisting pools of neural stem cells

These hormonal effects contribute to its potential anti-aging and stress-reduction benefits but also warrant caution for those with hormone-sensitive conditions

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