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When free radical production outpaces the body's antioxidant defenses a state known as oxidative stress cells accumulate damage that affects energy, immunity, skin health, and accelerates biological aging

The antioxidant is especially abundant in mitochondria, which cannot function without it

elegans model of polyQ aggregation and extends lifespan, reduces striatal atrophy and improves motor performance in the R6/2 mouse model of Huntingtons disease

"Patients will suffer from the usual side-effects of extreme tiredness, irrational behaviour, mood swings, memory problems." The British National Formulary, which sets guidelines for the use of vitamin B12 in pernicious anaemia, said the practice was based on the best available evidence base