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Description

Mol Cell 68(1):185-197.e6

doi: 10.4103/tcmj.tcmj_293_24 30 ChenZ.LinY.WangJ.YaoK.XieY.ChenX.et al

Given the existing differences in evidence strength and metabolic phenotypes among in vitro systems, animal models, and human studies, caution is still required when extrapolating these conclusions to clinical settings

Methods We conducted an untargeted 1 H NMR-based metabolomic analysis of serum in a clinically defined cohort of patients with genetic forms of PD (n = 119) and age- and sex-matched HCs (n = 48)