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The mice models behave normally without signs for pain, stress, or discomfort and did not lose any weight (Fig

For organoids, we next isolated using a protocol adapted from Mahe et al

During the coupling, non-ionic detergents like Tween-20 surfactant should not be present, as these will suppress the coupling

It has been postulated that neuronal expression of P-gp in the epileptic focus, leads to a decrease in the excitatory threshold facilitating seizure recurrence [27] and increasing the stressful conditions that trigger ferroptosis