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Therefore, although numerous small molecule drugs have been discovered for inducing and inhibiting ferroptosis, these drugs have not yet been translated into clinical applications to benefit patients

Notably, Retatrutide induced a robust rebound in the expression of several key oxidative enzymes that were profoundly suppressed by HFD, including Eci3 (8.51-fold), Cyp4a14 (5.44-fold), Cyp4a10 (5.05-fold), and Scd1 (4.61-fold)

( Aspergillus fumigatum in macrophages and in the experimental model of Aspergillosis (56)

In addition, high doses of vitamin D may have toxic effects, and routine screening should be conducted for patients with PCOS before recommending any supplements (26)