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Description

In the future, spinal cord targeting needs to be enhanced by improving drug delivery systems (such as nanocarriers or targeted modifications), optimizing dosage strategies in combination with pharmacokinetic-pharmacodynamics models, and promoting multi-stage clinical trials to clarify its clinical translational value

Gayam et al., An NAD(P)H:quinone oxidoreductase 1 (NQO1) enzyme responsive nanocarrier based on mesoporous silica nanoparticles for tumor targeted drug delivery in vitro and in vivo