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Meanwhile, certain viruses may employ epigenetic mechanismssuch as neuron-specific microRNAsto suppress transcription factors, promote viral genome heterochromatinization, and induce glial histone methylation, thereby establishing viral latency and altering synaptic gene expression (195, 196)

2 The sequencing established that the 112-amino-acid-long TGF-1 monomer is initially synthesized as the C-terminal segment of a 390-amino-acid-long precursor polypeptide