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An internal enzyme known as glutamine synthetase drives this process by taking glutamate and ammonia both naturally available in muscle tissue and assembling them in a reaction fuelled by adenosine triphosphate (ATP)

doi: 10.1038/sj.bjp.0707444 222 Ohno-ShosakuTKanoM

Redundancy in bacterial resistance to ROS is a relatively common phenomenon, including the need to eliminate five individual enzymes in Salmonella enterica Serovar Typhimurium to exhibit a phenotype in the presence of hydrogen peroxide (Hbrard et al., 2009) and simultaneous disruption of four enzymes in Bacillus anthracis to observe a phenotype in the presence of superoxide (Cybulski et al., 2009)

Finally, there was an increase in erectile dysfunction (ED) in male participants of the study (2)