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Pro and His have metal-binding, antioxidant, and signaling functions and can be accumulated in plants in response to different metals including As, Cd, Cu, Hg, and Ni (Kerkeb and Krmer, 2003

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Cell 75 : 241251 Kane DJ, Sarafian TA, Anton R, Hahn H, Gralla EB, Valentine JS, Ord T and Bredesen DE (1993) Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species