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Philip Kistler Stroke Research Center, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, USA, Boston, United States, 2 Center for Imaging Sciences and Medical Physics, Department of Medical Imaging, Hematology, and Clinical Oncology, Ribeirao Preto Medical School, University of So Paulo, So Paulo, Brazil, 3 Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA, Chicago, United States, 4 Department of Biomedical Engineering, Illinois Institute of Technology, Chicago, IL, USA, Chicago, United States, 5 MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA, Charlestown, United States Background and Aims: Cerebral Amyloid Angiopathy (CAA), characterized by amyloid- accumulation in leptomeningeal and cortical vessels, is a leading cause of intracerebral hemorrhage (ICH) lacking effective treatment options