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Due to a number of conditions, including also poor diet, and for the Schilling test

By promoting Nrf2 activation, omega-3 fatty acids enhance the bodys ability to regulate antioxidant response elementsspecific DNA sequences that facilitate the expression of protective antioxidant genes and phase II defense enzymes [121]

For example, SASP reduces GSH expression levels at the cellular level, which induces growth arrest in breast cancer cells and increase the efficacy of anticancer drugs, such as doxorubicin (83), similar to preclinical investigations in vitro and in vivo (84)