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CRISPR/Cas9-mediated targeting of ABCC1 in Cas9-expressing THP-1 cells using multiple sgRNAs re-sensitized them to BCL-2 inhibition, as ABCC1 -targeted cells were rapidly depleted upon Venetoclax treatment (Fig

10.1371/journal.pone.0048924 PLoS ONE 177 SpencerP

A doctor must document the need for treatment to increase the chance of approval

Mol Cell Proteomics 10:M111.011015 Moore HC, Unger JM, Phillips KA, Boyle F, Hitre E, Porter D, Francis PA, Goldstein LJ, Gomez HL, Vallejos CS et al (2015) Goserelin for ovarian protection during breast-cancer adjuvant chemotherapy