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Cancer cell 33(4):706-720.e9, 2018

In various experimental models, glutamine administration has been shown to reduce epithelial cell death and preserve or improve barrier function.[11-13] For instance, in an animal model of chemotherapy-induced intestinal damage, glutamine decreased the severity of intestinal injury perhaps through improved intestinal cell turnover and enhanced antioxidant activity.*[14] Muscle Tissue Preservation Of the 20 amino acids required for protein synthesis, glutamine is the most abundant

Fungal GSTs may have a pivotal role in protecting fungi against plant-derived toxic metabolites and ROS accumulating during infection at the host-pathogen interface

Moreover, NAC restored GSH homeostasis and reduced lipid peroxidation levels in fibroblasts obtained from skin biopsies from AMN and cALD patients, suggesting a potential for antioxidant-based approaches for treating ALD [115]