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Moreover, Foxo1 has a significant role in muscle regeneration, injury response, and modulating fiber type composition [19, 20]

Adult ganglion cells in mammals show little or no regenerative response after pressure injury however their survival can be extended for short periods of time with recombinant and virally expressed delivery of neurotrophic factors (e.g., BDNF, CNTF, NT-4, FGF-2, neurturin) which partially protect RGCs in animal models of glaucoma (59, 74)

However, certain individuals cannot absorb enough through diet alone, even with adequate intake

Antioxidants (Basel) 11:1613 Norman K, Ha U, Pirlich M (2021) Malnutrition in older adultsrecent advances and remaining challenges