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Description

8AC) using two outcome measures: (1) the number of axonal objects/total axon area, and (2) the average axonal object size

A clear concentration-dependent increase in cytogenetic damage was observed, with the Relative Abnormality Rate (RAR) increasing from 11.30 0.05% at 1 mM to 22.77 0.69% at 6 mM, accompanied by substantial increases in micronuclei formation, spindle disorientation, and chromosomal clumping