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We also noted that GSTO1 expression was higher in several colorectal cancer patient tumours as compared with normal colon tissue, consistent with our bioinformatics analysis (Supplementary Fig

Interestingly, an experimental study showed that an extended polyglutamine residue in the tobacco plant leads to the accumulation of mutated Htt protein, affecting plant growth, with several OCM proteins, including GTP cyclohydrolase I (GTPCH, involved in BH4 metabolism in animals) were severely reduced in affected roots

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Efficacy and tolerability of guanylate cyclase-C agonists for irritable bowel syndrome with constipation and chronic idiopathic constipation: a systematic review and meta-analysis