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On the other hand, certain lncRNAs function as transcriptional repressors by blocking the binding or recruitment of transcription factors and RNA polymerase to gene promoters

478 These mechanisms operate synergistically to modulate muscle activation patterns, joint stiffness, and dynamic stability, ensuring that the musculoskeletal system can adapt efficiently to both anticipated and unexpected perturbations

Interestingly, 1-week post-treatment, GFAP expression was reduced to ~49% in untreated and ~28.8% in LPC-treated slices, suggesting mitigation of the astroglial response