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Since vitamin E is an efficient ROS-scavenging antioxidant, it is rational to assume that increased doses of this vitamin could help prevent chronic diseases

Dual-luciferase reporter assay To assess SRF-dependent transcriptional activation of PARN, the wild-type PARN promoter ( PARN -WT) was cloned upstream of the firefly luciferase gene

The Mann Whitney test (two-tailed) was used to determine the significance between two groups

Fly strains UAS-GFP (Bloomington Stock #6874), TH-Gal4 (Bloomington Stock #8848), CatalaseRNAi (Bloomington Stock #34020) and PHGPx (Bloomington Stock #33939), were obtained from Bloomington stock center, Indiana, along with park 13 (Bloomington Stock #79210) as the Parkinsonian disease model