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Extensive research confirms that it effectively alleviates hepatic steatosis, a process thought to be mediated by the activation of the hepatic AMPK signaling pathway

The Transsulfuration Pathway For an overview of the methylation cycle (aka methionine cycle) starting with homocysteines conversion to methionine through the methionine synthase (MS) and betaine homocysteine-S-methyltransferase (BHMT) reactions see the end of article 2 in this series

Participants in the study also showed reductions in malondialdehyde, a marker of cell damage in the liver

De Leo E, Elmonem MA, Berlingerio SP, Berquez M, Festa BP, Raso R, Bellomo F, Starborg T, Janssen MJ, Abbaszadeh Z, Cairoli S, Goffredo BM, Masereeuw R, Devuyst O, Lowe M, Levtchenko E, Luciani A, Emma F, Rega LR (2020) Cell-based phenotypic drug screening identifies luteolin as candidate therapeutic for nephropathic cystinosis