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Some patients may achieve adequate glycemic control or weight loss at this dose level, particularly those with mild metabolic dysfunction or those who are particularly sensitive to the medications effects

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Market-readiness is a long way off It remains uncertain, though, when these artificial beta cells will reach the market

Meanwhile, correlation analysis between MANF level and clinical variables in ICC showed that high expression of MANF was associated with larger tumor diameter ( P = 0.026), TNM stage ( P = 0.000), and distant metastasis ( P = 0.017) (Supplementary Table 1)