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A larger follow-up RCT (n=72 older adults) confirmed these findings, additionally demonstrating improvements in gait speed (+0.14 m/s), grip strength, 6-minute walk distance, waist circumference reduction, and systolic blood pressure reduction (Kumar et al., J Gerontol A Biol Sci Med Sci, 2023) [21]

Calcium-dependence of synexin binding may determine aggregation and fusion of lamellar bodies

The active site Cys31 and Cys86 of Grx-1 operate in MerA interactions and both Cys are required for MerA reactivation

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