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Clinical translation of this co-delivery system faces challenges in scalability and biocompatibility validation

Gut microbiota-derived components (e.g., LPS, peptidoglycan) and metabolites (e.g., SCFAs, TMAO) interact with hepatocytes via the portal vein, influencing glucose and lipid metabolism, immune responses, and redox balance, thereby driving MAFLD progression 118

Caution For adults only