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It binds to glycine receptors in the spinal cord and brainstem, producing calming effects

Symptoms of a vitamin B12 deficiency include: Anemia Fatigue and weakness Dizziness Memory loss or concentration Rapid heartbeat Excessive bruising Soreness of the mouth or tongue Although there is no solid medical research to support these claims, many people believe that Vitamin B12 is helpful in improving concentration and boosting energy, as well as preventing or improving the following conditions: macular degeneration, a weakened immune system, infertility, sleep disorders, allergies, asthma, skin disorders and heart or kidney problems

People who take certain medications may also be at risk of vitamin B12 deficiency, including, but not limited to, estrogen, H2 receptor antagonists, PPIs (Proton Pump Inhibitors), Chloramphenicol, and Metformin

Overall, for the vast majority of patients, biotin supplementation (whether oral or via injection) is free of significant side effects