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MIC shots combine Methionine, Inositol, Choline, and B12

Dysregulated metabolism of fatty acids results in modifications to the composition of membrane lipids, potentially heightening vulnerability to peroxidative damage

AD gene expression profiles were acquired from the Gene Expression Omnibus (GEO) database, with a specific focus on data generated using the Illumina HumanHT-12 V4.0 Expression Microbead Chip platform (accession number: GSE52093)

Approximately 150 g of digested peptide from each sample was used for purification, which is within the C18 spin columns maximum binding capacity of 100 g (#744101, Harvard Apparatus, Holliston, MA, USA) and then lyophilized before being analyzed on the Orbitrap Fusion Tribrid mass spectrometer coupled with an Ultimate 3000 nano-UPLC system (Thermo Fisher Scientific, Waltham, MA, USA)