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Rather than focusing on a single area of investigation, it has become relevant to studies spanning biochemistry, molecular signalling, connective tissue biology and extracellular matrix research

Together these findings suggest that the elimination of senescent cells through vaccination targeting GPNMB-expressing cells could be beneficial to health span and possibly extend lifespan

A compound can be widely discussed and still rest almost entirely on cell-culture and animal data, with little or no controlled human evidence

Their combined action targets multiple metabolic pathways involved in energy intake, glucose metabolism, and fat storage