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The STEP 1 trial, published in the New England Journal of Medicine , demonstrated that participants receiving semaglutide 2.4 mg weekly lost an average of 14.9 percent of their body weight over 68 weeks, compared to 2.4 percent with placebo (Wilding et al., 2021)

The organism is capable of elaborating exotoxins that bind to receptors on intestinal epithelial cells, leading to inflammation and diarrhea.4 QT Prolongation Fluoroquinolones can cause arrhythmias due to QT prolonging effects that may be augmented if given together with any of the multiple other drugs, such as amiodarone, that cause QT prolongation