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As these are water-soluble vitamins, any excess intakes are obviously excreted out of the body through urination

Over the following 6 to 8 days, the concentration gradually declines as your body metabolizes the compound, primarily through hepatic pathways that do not interact with cytochrome P450 enzymes

Practical tips for taking it To get the best possible effect from your oral B12 supplement, follow these recommendations: Take on an empty stomach: For best absorption, you should take your B12 supplement in the morning before breakfast or between meals with a glass of water

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