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This study noted a distinct level of activity between exposed animals pretreated with CRE, CRE-AgNPs, and those without treatment

Biomed Chromatogr 2009;23:658-64

A case example of a radiation-relevant adverse outcome pathway to lung cancer

Animal studies suggest that reducing NNMT activity may: increase cellular energy expenditure improve metabolic efficiency reduce fat accumulation influence NAD metabolism These findings have made NNMT a potential therapeutic target for metabolic disease research