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Originally identified by Loren Pickart in human plasma, GHK-Cu has been the subject of extensive cellular biology and biochemical research literature for over five decades, with research contexts examining tissue biology, cellular signaling pathways, copper-binding peptide chemistry, and extracellular matrix research

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The effect of copper tripeptide and tretinoin on growth factor production in a serum-free fibroblast model

Acute Lung Injury Protection Acute lung injury protection in LPS-induced mouse models shows: Pulmonary fibrosis studies using bleomycin-induced injury demonstrate reduced inflammatory cell infiltration, reduced interstitial thickness, and reduced TNF- and IL-6 expression at doses of 2.6-260 g/mL/day