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Br Med J 2:478479 Rumack BH (1984) Acetaminophen overdose in young children

In a late-onset familial AD (FAD) mouse model, H3K9 dimethylation (H3K9me2) and histone methyltransferase 1 (EHMT1) and EHMT2 were significantly increased in the prefrontal cortex, a key cognitive region in AD (Zheng et al., 2019)

102 It has a novel mode of action that is distinct from that of other tubulin inhibitors: it terminates microtubule elongation to trigger cell death with no effect on microtubule depolymerization