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In the following sections, we delineate the mechanisms and regulatory dimensions governing these astrocytic state transitions and their contributions to reactive diversity under environmental stressors and pathological challenges

470 In this study, researchers randomized 529 patients with heart failure with a preserved ejection fraction and body mass index (weight in kilograms in the square of the height in meters) 30 to receive once-weekly injections of semaglutide (2.4 mg) or placebo for 52 weeks