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How This Works IGF-1 DES is a naturally-shortened variant of IGF-1: removing the N-terminal Gly-Pro-Glu tripeptide (and specifically the glutamate at position 3) greatly weakens its affinity for the IGF-binding proteins that normally sequester circulating IGF-1 [1]

(1998) cites an instance where a large number (25, including 4 gravid females) of North American Green Frogs were caught on land near a wetland during a cold snap in northern Wisconsin

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