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doi: 10.1016/j.colsurfb.2018.03.018

2.5 Combination studies MDA-MB-468 cells were harvested and plated (2.5 $\times$ 10 4 per well) in 96-well plates for 24 h

Thats true for classically regulated drugs and medications, where the FDA has approved the drug, the manufacturing methods, and even the labeling on the bottle and the box