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Physicians therefore evaluate each patients health status before recommending NAD+ injections and exercise caution in certain scenarios even in the absence of formal contraindication labels

Recently, increased IGF-I expression was reported in obese children with non-alcoholic fatty liver disease (NAFLD) and it was combined with upregulation of IGF1R (96), not expressed in the normal liver but involved in liver repair, such as after liver resection in a mouse model (97)