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Feature · Product Review
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Description

In this work we have engineered a panel of BiTE-like albumin fusions with extended circulatory half-life programmed by the FcRn affinity of the albumin sequence that exhibit improved anti-tumour effects in a beyond state-of-the-art animal model

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DFP and deferasirox (DFX) display improved BBB penetration but carry potential hepatotoxicity and agranulocytosis risks, restricting long-term use (Devos et al., 2014)

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It is not intended for consumption or clinical application

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Manning AM

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