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Owing to their ability to cross the BBB, regulate neuroinflammation, and repair damaged tissues, MSCs have emerged as promising candidates in the treatment of neurodegenerative diseases and epilepsy-related conditions

In recent years, research on ferroptosis in the field of ophthalmology has gradually emerged, and a large amount of evidence has shown that it is closely related to the occurrence and development of ophthalmic diseases such as age-related macular degeneration (AMD), diabetic retinopathy (DR), retinal ischemiareperfusion injury (RIRI), retinitis pigmentosa, dry eye disease, cataracts, and glaucoma

Fasted plasma creatine ranged from 45.8 to 137.0 mol/L with an average concentration of 83.0 24.7 mol/L, therefore the reference range was determined to be 33.6132.4 mol/L (mean 2 SDs)

The gene spans the length of 8552 nucleotides with 10 exons