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Moreover, two cross-sectional studies assessing urinary PAHs concentrations in adults (Yang et al., 2016) and blood PAHs DNA adducts in newborns found associations with lower total BDNF levels (Perera et al., 2015)

Through a variety of mechanisms, including the inhibition of pathogen colonization, the induction of antimicrobial peptides production and mucus secretion, the increase of IgA production, the downregulation of the Th17 and pro-inflammatory cytokines like IL-17F and IL-23, and the up-regulation of Tregs, probiotic consumption in the form of fermented foods can improve gut barrier integrity, gut immunity, and maintain gut homeostasis (Shahbazi et al., 2020)

Discussion Targeting cell cycle through cyclin-dependent kinases 4 and 6 (CDK4/6) inhibition (CDK4/6i) is an established strategy in the treatment of several cancer types [3]

Glutathione helps to mitigate inflammation by neutralizing free radicals and regulating inflammatory cytokines