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doi: 10.1016/j.jep.2024.117899, 62

T and B lymphocytes both originate from lymphoid precursors in the bone morrow, but whereas B cells complete their maturation in the bone marrow, before entering the circulation, T cells leave the bone marrow at an immature stage and migrate to the thymus where they mature [28]

In another study, glioblastoma cell lines that had higher xanthine and hypoxanthine levels were more likely to develop radiotherapy resistance when compared to cell lines with lower xanthine levels [66]