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This is a potential research area but isnt a current clinical option

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While sertraline is generally well-tolerated, it can cause side effects, including: Nausea Headache Insomnia or drowsiness Dizziness Dry mouth Fatigue Changes in appetite Sexual dysfunction Weight changes Potential for increased anxiety or agitation, especially during the initial weeks of treatment What Are the Full Benefits of Sertraline

Expected efficacy and side effects Common side effects of semaglutide with glycine may include nausea, diarrhea, constipation, abdominal discomfort, and heartburn