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doi:10.3233/JAD-160633 9

Thus by way of example the interval between the first and second administration may be around 2 months and the interval between the second and the third administration may be around 7 months

The ratio of Firmicutes to Bacteroidetes is a commonly-studied change with an increase often linked to HFD consumption/obesity in mice 43,44 and humans 45,46 (for review, see John and Mullin, 2016 47 )