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parapsilosis W23 cultures (1x10 7 cells/ml) was first added to a black glass-bottomed 96-well plate (Grenier) followed by pre-warmed RPMI 1640 in the ratio 1:10 and incubated shaking for 24 h at 20 rpm (37C)

The mitochondrial thioredoxin system may be essential for mammalian development because disruption of Trx2 gene in the mouse resulted in massive apoptosis during early embryogenesis and embryonic lethality [166]