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However, TGF-1 has two sides: In addition to being an inducer driving fibrotic and anti-inflammatory responses, its inactivation may also mean exacerbating proinflammatory effects, suggesting that antifibrotic intervention that directly targets TGF- may trigger other unknown risks (145)

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Reference Evans, OBrien, Ma, Hager, Riggins, Lambert and Riechers2017

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