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COVID-19: gastrointestinal manifestations and potential fecaloral transmission

Renal fibrosis, characterized by tubulointerstitial fibrosis and glomerulosclerosis, is the typical outcome of CKD, and represents a growing public health burden and is the leading cause of ESRD [4, 5]

Sodium/hydrogen exchanger 3 (NHE3) inhibitor (Tenapanor): Shown to reduce abdominal pain and bloating in IBS-C by modulating sodium transport and visceral sensitivity, though long-term safety remains under investigation [114,115,116]

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